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Medical Article Detail
PERIOD JOURNEY of DIABETES
Published On :
April 10, 2009
http://www.diabetesheartcare.com/admin/RTE_popup_word_pashttp://www.diabetesheartcare.com/admin/RTE_popup_word_paste.aspte.asp
PERIOD JOURNEY OF Diabetes Mellitus
PERIOD
THE Concerns
METHODS
OUTCOME
Pre 1923
( In the times of Gandhi & Nehru ,Hitler ), & our Grandparents
The Patients who develop diabetes wait for death , because of no treatment available except Starvation
Use of various Bitters , Herbs , Spiritual healing etc.
NO MEDICAL
TREATMENT WAS
AVAILABLE
Certain mortality, physician tool less,Helpless
but curious !!
1923 1946
(In times of , Vajpai ,Gandhi & Nehru) & our
Parents
SURVIVAL for few years
Crude Pancreatic extracts , unpurified Insulin of animal origin ,used for injecting , without a clue about
control , or relief.
STILL NO ORAL
ANTIDIABETIC s !!
Only
short term survival
, with hardly any relief from symptoms .
Physician Helpless BUT hopeful !!
1947 1956
( the times of Indira,Radhkrishnan,Nehru
Shastri , ) & our Parents ,
Relief from Ketoacidocis ,Osmotic symptoms , infections , leading to increased survival.
Pharmaceutical injectible Insulin but Unpurified , high Insulin allergy,
First Oral drug Restinon became available
Much better control , & survival BUT still
Insulin the ONLY OPTION for every diabetic
Physician waiting for OHA s arrival eagerly
1957 1980 ( The Times of our Parents , & our early days and education years)
Better Quality of Life for Diabetics, prevention of Infections , Diabetic Coma , Retinopathy & possibly Heart Attack & Brain Stroke
Glycemic Control with OHAs in Type 2 DM (called NIDDM ) & more purified Animal insulins & better insulin syringes for IDDM,self monitoring of urine sugar by test tube test,MANY MORE Long & short acting OHAs became available : Glibeclamide , Metformin etc,
Much better QOL
with long acting OHAs and Long acting insulins.
BUT Cardiovascular & Micro vascular complications not under check,not monitored , and
high rate of Disability .
Physician equipped but not with Instant Research & Knowledge
1981 1995
( The Times of our own , the Early IT days,)
Prevention of Micro & Macro vascular Complications , Self Monitoring of Blood Glucose.
With DCCT, KumoMoto, & UKPDS , Significance of TIGHT Glycemic control was understood and ,
Handy Glucose Meters came,HUMAN synthetic Insulins , Insulin Pens , & HbA1c became available.& came ACE Inhibitors
Role of Insulin in Type 2 DM was first time understood and publicised,
MIROALBUMINURIA
was started as periodic evaluation,
ACTUALLY the RICHEST 15 years since 1923 !!
More & More Patients empowered to self monitoring, better Doctor Patient
Co ordination,
Physician much better with Tools for INFO & THERAPY
1996 2003
( Times of present generation , IT Revolution , Fast Developments ,Very Fast Urbanization,Indian MNCs,BPOs .........)
Cardiovascular Safety , Reduction of Morbidity , Mortality from T2DM ,
The WHO Projection of Number of Diabetics in World vs. India , HOPE trial , Primary prevention of Diabetes taken up as Priority by NGOs a over the Globe,RAMIPRIL came, and came better , safer OHAs, and the GLITAZONES .The Lifestyler Insulin Analogues Pumps came , Type 2 DM was established as CAD equivalent ( the vascular disease ) , THE EXTRAVAGANT but
Hi Tech era that is continuing !
No Primary Prevention appeared anywhere near Due to Rampant Urbanisation of eating and transportation behaviour,though better secondary & Tertiary prevention achieved
Physician ? getting Carried away by M Forces & Indiscreet INFO.
2004 2008 / 9
( The Overdrive Mode , Difficult waters )
2009 FORWARDS...
our children,
juniors
Questions on CV Safety of the agents touted tobe CV Protectors ,
SAFE Drugs,
OBESITY prevention &
Treatment,
FDA under Cloud. Physician confused and disgusted in regard to Glitazones,Rimonabent, & Exenatide, DPP4 inhibitors introduced ,The Intensive Glycemic Lowering in Critical care as well as Chronic care is without the clear guidelines due to conflicting results & Doctored conclusions from so called Landmark Trials.
THE DIFFICULT TIMES FOR Diabetologist
Tightening of scews on
M Forces , More Real Life, evidence base trials,
Resetting of Priorities, WE NEED ORAL INSULIN , PORTAL Delivery of Insulin , SAFE Anti Obesity Drugs , Safe & Affordable BARIATRIC SURGERY,
STEM CELL Rx.
BUT More than that .......
THE BALANCED
LIFESTYLE ....... &
ATTITUDE .
Time for the physician to think , Plan & Act with own updated knowledge,superimposed with guidelines from apex organizations and extrapolate carefully to our own patient type, Be Ware of M Forces !!!!!
HUM HONGE
KAAMIAAB !!
MORAL OF THE STORY IS
..
Please send in your own honest 10 100 words,
All will be acknowledged , shared and a Cautious Intelligent Physician Group might emerge !!
Eagerly waiting for your inputs .
Dr.Vinod K Gujral
vkg28@hotmail.com
www.diabetesheartcare.com
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